Its about time we got one of these threads!!
+10 Mothers - Any meal
Bouchon - Thomas Kellar Restaurant - Fantastic Breakfast/Bakery
L'Atelier De Joel Robuchon - Tasting Menu is pricey, but worth every bite
Joe's Stone Crab- Amazing Steak and Real Key Lime Pie
+1 Shiros - actually... +20 - Still have not had better sushi to date, even in Asia. Be sure to sit at the sushi bar, there is no other way to eat there.
+1 Spinasse - Great Pasta, Cool atmosphere
Canon - Best Cocktail Bar and selection you will find, hands down in Seattle... arguably one of the best in the country.
Rob Roy - Great cocktails right down the block from Shiros (great dinner combo there)
Zig Zag Cafe - Great Cocktails
New York City:
Grimaldi's Pizza - Best Pizza in NYC
Marie Belle - Chocolate, Chocolate, Chocolate! Get the Aztec sipping hot chocolate, it will change your life.
Stingray - Great Sushi, Modern atmosphere and good sake choices - a staple every time.
more to come......