Sometimes your dreams need to get crushed a few times to build you into a stronger person. Life is hard and most of us have been there.
If you’re sick of living in an area and aren’t saddled with mortgage payments, crippling debt or a family then maybe it’s time to pick up and move. Go where you want to be and figure out what you need to do to make a living. If you hate where you are, and what you’re doing, and then get tied down in that situation you’ll regret it more than moving to another city and taking a job at 1/3rd your salary just to start back up somewhere else.
I have friends that just picked up and moved, might have taken them a few months but they knew the market was better where they were going and got new gigs.