Denver is a desirable location, and be prepared to look outside of the role of Industrial Designer if you want to work there. It is growing at an accelerated rate. I have several friends who work there.
I would contact iDSA to help you with local intel for each region you are considering.
I heard TTI Floor-care is relocating Designers to Charlotte NC, which is also a perennial choice for “quality” of life
I currently live and work in Chicago.