Do you have a place to stay yet?
Some of my faves:
1_ The Maritime: http://www.themaritimehotel.com
2_ The Ace Ace Hotel New York | Boutique Hotel in Midtown Manhattan NYC
3_ The Standard Highline:
http://book.standardhotels.com/?rt=google|cpc|ABZ02-The-Standard-High-Line-Brand|standard%20hotel%20high%20line&gclid=CjwKEAjwwN-rBRD-oMzT6aO_wGwSJABwEIkJ552GTDQarkUREgXKcLonpgGhtZLWerDzkszZRmJgIxoCaCrw_wcB#lp-pom-block-10
Definitely check out the high line.