An SSD is the best choice for the OS drive. USB Flash sticks do not have the same overall performance as a SATA hard disk, so it would cause issue when running certain types of programs that prefer random writes, etc.
An SSD is the best choice for the OS drive. USB Flash sticks do not have the same overall performance as a SATA hard disk, so it would cause issue when running certain types of programs that prefer random writes, etc.